疾病的影响远不止身高。患儿常伴随中耳炎、脊柱侧弯、关节功能异常等并发症，严重的枕骨大孔狭窄甚至可能压迫脊髓、导致呼吸暂停，存在致命风险。
Surgeons at Russells Hall Hospital in neighbouring Dudley later had to amputate both of her legs below the knee, as well as both of her hands, due to the spread of the condition.
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