在医学上，青春期并不是一个模糊的概念。自20世纪中期以来，儿科和内分泌学界主要通过几类指标来判断青春期的启动时间：女孩乳房发育的起始（thelarche）、阴毛出现，以及第一次月经（初潮，menarche）。这些体征被系统地纳入性成熟评定分期体系（ Tanner ），并长期作为国际通用的临床评估工具。
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Drums, chants and celebrations as Ethiopians mark the baptism of Jesus